Liposarcoma is the most common sarcoma of the soft tissues in adults, accounting for 10% to 18% of all soft tissue sarcomas in different series. Liposarcoma is most frequently found in the extremities and the retroperitoneum. Its occurrence in head and neck is rare. Head and neck liposarcomas account for between 3% and 5.6% of all liposarcomas. Laryngeal and hypopharyngeal liposarcomas are exceedingly rare; to the best of our knowledge, there are fewer than 40 well-documented cases reported to date. We present a case of a 60-year-old woman with a history of hoarseness and dysphagia. Direct laryngoscopy showed a polypoid growth on the right vocal cord. Biopsy of the laryngeal mass was performed and submitted for histologic examination, which was consistent with round cell liposarcoma.