Skip to main content
Candida esophagitis: Risk factors in non-HIV population in Pakistan
World Journal of Gastroenterology
  • Javed Yakoob, Aga Khan University
  • Wasim Jafri, Aga Khan University
  • Shahab Abid, Aga Khan University
  • Nadim Jafri, Aga Khan University
  • Muhammad Islam, Aga Khan University
  • Saeed Hamid, Aga Khan University
  • Hasnain Ali Shah, Aga Khan University
  • Akbar S Hussainy, Aga Khan University
Publication Date
Document Type
AIM: Candida esophagitis is a frequent infection in immunocompromised patients. This study was designed to determine its characteristics in non- human immune deficiency virus (HIV) infected patients attending a teaching hospital. METHODS: Clinical records of all patients coded by international classification of diseases 9th revision with clinical modifications' (ICD-9-CM), with candida esophagitis diagnosed by esophagogastroduodenoscopy (EGD) and histopathology over a period of 5 years were studied. RESULTS: Fifty-one patients (27 males, 24 females, range 21-77 years old and mean age 52.9 years) fulfilled the criteria (0.34% of the EGD). The common predisposing factors were carcinoma (OR 3.87, CI 1.00-14.99) and diabetes mellitus (OR 4.39, CI 1.34-14.42). The frequent clinical symptoms were retrosternal discomfort, dysphagia and epigastric abdominal pain with endoscopic appearance of scattered mucosal plaques. Another endoscopic lesion was associated with candida esophagitis in 15% patients. CONCLUSION: Carcinomas, diabetes mellitus, corticosteroid and antibiotic therapy are major risk factors for candida esophagitis in Pakistan. It is an easily managed complication that responds to treatment with nystatin.
Citation Information
Javed Yakoob, Wasim Jafri, Shahab Abid, Nadim Jafri, et al.. "Candida esophagitis: Risk factors in non-HIV population in Pakistan" World Journal of Gastroenterology Vol. 9 Iss. 10 (2003) p. 2328 - 2331
Available at: