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Article
Factors determining the clinical outcome of acute variceal bleed in cirrhotic patients.
Indian Journal of Gastroenterology : official Journal of the Indian Society of Gastroenterology
  • Shahid Majid, Aga Khan University
  • Zahid Azam, Aga Khan University
  • Hasnain Ali Shah, Aga Khan University
  • Mohammad Salih, Aga Khan University
  • Saeed Hamid, Aga Khan University
  • Shahab Abid, Aga Khan University
  • Wasim Jafri, Aga Khan University
Publication Date
5-1-2009
Document Type
Article
Disciplines
Abstract
Variceal bleed is a severe complication of portal hypertension. We studied the predictors of failure to control variceal bleed and re-bleed in Patients with cirrhosis. We reviewed the case records of 382 consecutive Patients admitted with variceal bleed from January 2001 to December 2005. Diagnosis of cirrhosis was made on clinical, laboratory, and radiological parameters. Acute variceal bleeding, failure to control bleed, and re-bleeding were defined according to Baveno III consensus report. Failure to control bleed was observed in 39 (10.2%) Patients while in hospital re-bleed occurred in 49 (12.8%) Patients. Thirty-four Patients died. Diabetes was present in 148 (39%) Patients. On multivariate logistic regression analysis, predictors of failure to control bleed were presence of diabetes mellitus and active bleeding at the time of endoscopy, predictors of in-hospital re-bleed were diabetes mellitus and serum bilirubin >3 mg/dL. Diabetes mellitus, active bleeding at endoscopy and bilirubin >3 mg/dL are bad prognostic factors for initial control of variceal bleed, and recurrent bleed in Patients with cirrhosis.
Citation Information
Shahid Majid, Zahid Azam, Hasnain Ali Shah, Mohammad Salih, et al.. "Factors determining the clinical outcome of acute variceal bleed in cirrhotic patients." Indian Journal of Gastroenterology : official Journal of the Indian Society of Gastroenterology Vol. 28 Iss. 3 (2009) p. 93 - 5
Available at: http://works.bepress.com/shahab_abid/19/