Article
Solid-Phase Synthesis of Tris-heteroleptic Ruthenium(II) Complexes and Application to Acetylcholinesterase Inhibition
Inorganic Chemistry
(2008)
Abstract
A synthetic route with two consecutive coordination chemistry steps on a solid support affords tris-heteroleptic ruthenium(II) polypyridyl complexes with high purity and in good yields. As an application we report the identification of a nanomolar acetylcholinesterase inhibitor from a small ruthenium complex library synthesized on Lanterns.
Disciplines
Publication Date
Winter March 29, 2008
Citation Information
Seann P. Mulcahy. "Solid-Phase Synthesis of Tris-heteroleptic Ruthenium(II) Complexes and Application to Acetylcholinesterase Inhibition" Inorganic Chemistry Vol. 47 Iss. 12 (2008) Available at: http://works.bepress.com/seann_mulcahy/7/