Article
Australian clinical practice guidelines for the diagnosis and management of Barrett's Esophagus and Early Esophageal Adenocarcinoma
Journal of Gastroenterology and Hepatology
(2015)
Abstract
Barrett’s esophagus (BE), a common condition, is the only known precursor to esophageal
adenocarcinoma (EAC). There is uncertainty about the best way to manage BE as most
people with BE never develop EAC and most patients diagnosed with EAC have no
preceding diagnosis of BE. Moreover, there have been recent advances in knowledge and
practice about the management of BE and early EAC. To aid clinical decision making in
this rapidly moving field, Cancer Council Australia convened an expert working party to
identify pertinent clinical questions. The questions covered a wide range of topics including
endoscopic and histological definitions of BE and early EAC; prevalence, incidence,
natural history, and risk factors for BE; and methods for managing BE and early EAC. The
latter considered modification of lifestyle factors; screening and surveillance strategies;
and medical, endoscopic, and surgical interventions. To answer each question, the working
party systematically reviewed the literature and developed a set of recommendations
through consensus. Evidence underpinning each recommendation was rated according to
quality and applicability.
Disciplines
Publication Date
2015
DOI
10.1111/jgh.12913
Citation Information
Whiteman, D., Appleyard, M., Bahin, F., Bobryshev, Y., Bourke, M., Brown, I., Chung, A., Clouston, A., Dickins, E, Emery, J., Eslick, G., Gordon, L., Grimpen, F., Hebbard, G., Holliday, L., Hourigan, .L, Kendall, B., Lee, E., Levert-Mignon, A., Lord, R., Lord, S., et al. (2015). Australian clinical practice guidelines for the diagnosis and management of Barrett's Esophagus and Early Esophageal Adenocarcinoma. Journal of Gastroenterology and Hepatology, 30(5), 804-820. DOI: 10.1111/jgh.12913