Mixed-race persons constitute a substantial and growing population in the United States. We examined multiracial college students’ experiences with prejudice and discrimination in college with conducted focus group interviews with 12 mixed-race participants and individual interviews with 22 mixed-race undergraduates to understand how they experienced prejudice and discrimination during their college careers. Analysis revealed 7 types of multiracial prejudice and discrimination which were confirmed by individual interviews: (a) racial essentialization, (b) invalidation of racial identities, (c) external imposition of racial identities, (d) racial exclusion and marginalization, (e) challenges to racial authenticity, (f) exoticization, and (g) pathologizing of multi-racial individuals. Implications for research and practice are discussed.