Article
CDK4 Inhibitors Thwart Immunity by Inhibiting Phospho-RB-NF-κB Complexes
Molecular Cell
Document Type
Article
Publication Date
1-3-2019
URL with Digital Object Identifier
10.1016/j.molcel.2018.12.012
Abstract
PD-L1 plays a central role in immune recognition of cancer cells. In this issue of Molecular Cell, Jin et al. (2019) report that a phosphorylated retinoblastoma protein contacts the DNA-binding domain of p65 NF-κB, thereby blocking transcription of PD-L1.
Citation Information
Seung J. Kim, Samuel Asfaha and Frederick A. Dick. "CDK4 Inhibitors Thwart Immunity by Inhibiting Phospho-RB-NF-κB Complexes" Molecular Cell Vol. 73 Iss. 1 (2019) p. 1 - 2 Available at: http://works.bepress.com/samuel-asfaha/6/