Article
Antinociceptive Activity of Zizyphus spina-christi Root Bark Extract
Fitoterapia
Document Type
Article
Publication Date
5-1-2001
DOI
http://dx.doi.org/10.1016/s0367-326x(00)00289-6
PubMed ID
11395256
Abstract
The antinociceptive effect of the aqueous extract of Zizyphus spina-christi root bark was investigated in mice and rats. Acetic acid-induced writhing, formalin and thermal (hot plate) tests were used. The extract (50 and 100 mg/kg, i.p.) showed a dose-dependent analgesic effect in all the tests used. Its i.p. LD50 in mice was 2236.07 mg/kg.
Disciplines
Keywords
- Zizyphus spina-christi,
- Antinociceptive activity
Citation Information
B. Adzu, Samson Amos, C. Wambebe and K. Gamaniel. "Antinociceptive Activity of Zizyphus spina-christi Root Bark Extract" Fitoterapia Vol. 72 Iss. 4 (2001) p. 344 - 350 ISSN: 0367-326X Available at: http://works.bepress.com/samson_amos/44/
Journal also known as Fitoterapia: The Journal for the Study of Medicinal Plants