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Article
Metastatic signet ring gastric adenocarcinoma presenting with microangiopathic hemolytic anemia.
Indian Journal of Gastroenterology
  • Natasha Ali, Aga Khan University
  • Nausheen Kamran, Aga Khan University
  • Salman Adil, Aga Khan University
  • Shahid Pervez, Aga Khan University
Publication Date
7-1-2007
Document Type
Article
Abstract

Metastatic adenocarcinoma presenting as microangiopathic hemolytic anemia (MAHA) and leukoerythroblastic blood picture is rare. We report three patients who presented with MAHA as the initial symptom of metastatic signet ring cell gastric adenocarcinoma. One patient had past history of gastric ulcer. In all these patients the initial diagnosis was based on peripheral blood smear followed by bone marrow biopsy; upper GI endoscopy showed presence of gastric ulcers with focally scattered neo-plastic signet ring cells on histopathology. All patients died within a week of diagnosis.

Citation Information
Natasha Ali, Nausheen Kamran, Salman Adil and Shahid Pervez. "Metastatic signet ring gastric adenocarcinoma presenting with microangiopathic hemolytic anemia." Indian Journal of Gastroenterology Vol. 26 Iss. 4 (2007) p. 185 - 186
Available at: http://works.bepress.com/salman_adil/8/