Maintenance of cognitive performance and mood for individuals with Alzheimer's disease following consumption of a nutraceutical formulation: a one-year, open-label studyJournal of Alzheimer's Disease (2016)
Nutritional interventions have shown varied efficacy on cognitive performance during Alzheimer’s disease (AD).
Twenty-four individuals diagnosed with AD received a nutraceutical formulation (NF: folate, alpha-tocopherol, B12, S-adenosyl methioinine, N-acetyl cysteine, acetyl-L-carnitine) under open-label conditions (ClinicalTrials.gov
NCT01320527). Primary outcome was cognitive performance. Secondary outcomes were behavioral and psychological symptoms of dementia (BPSD) and activities of daily living. Participants maintained their baseline cognitive performance and BPSD over 12 months. These findings are consistent with improvement in cognitive performance and BPSD in prior placebo-controlled studies with NF, and contrast with the routine decline for participants receiving placebo.
- Alzheimer’s disease,
- behavioral symptoms,
- cognitive performance,
- nutraceutical formulation
Citation InformationRuth Remington, Cynthia Bechtel, David W. Larsen, Annemarie Samar, et al.. "Maintenance of cognitive performance and mood for individuals with Alzheimer's disease following consumption of a nutraceutical formulation: a one-year, open-label study" Journal of Alzheimer's Disease (2016)
Available at: http://works.bepress.com/ruth_remington/25/
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