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About Rupesh Kotecha

Rupesh Kotecha, M.D., is a board-certified radiation oncologist at Miami Cancer Institute. Dr. Kotecha is the Chief of Radiosurgery and has specialized training and experience in utilizing the latest techniques in radiation therapy treatment for both cancer and noncancerous conditions. His research background and clinical interests have primarily focused on the treatment of patients with stereotactic radiotherapy, including CyberKnife®, LINAC-based and GammaKnife® radiosurgery, and stereotactic body radiation therapy (SBRT) or stereotactic ablative radiotherapy (SABR). He also specializes in advanced radiation therapy treatment techniques, including re-irradiation, proton beam radiotherapy, and MR-guided radiation therapy. He also has unique expertise in cardiac radiosurgery, an emerging non-invasive procedure for patients with cardiac arrhythmias. During medical school, Dr. Kotecha was inducted into the Alpha Omega Alpha Honor Medical Society, an organization that recognizes excellence in scholarship and the profession of medicine. He has been an invited speaker at numerous national and international symposiums, and has published multiple book chapters and dozens of articles in peer-reviewed journals, including the Journal of Clinical Oncology, International Journal of Radiation Oncology Biology Physics, Cancer, and Practical Radiation Oncology. He is an editorial contributor on the topic of brain cancer for Practice Update, an online resource for healthcare providers throughout the United States and around the world.

Positions

2020 - Present Director, Central Nervous System Metastasis Program, Baptist Health South Florida ‐ Miami Cancer Institute
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2018 - Present Chief, Radiosurgery, Baptist Health South Florida ‐ Miami Cancer Institute
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November 2017 - Present Assistant Professor, Florida International University ‐ Herbert Wertheim College of Medicine
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August 2017 - Present Radiation Oncologist, Baptist Health South Florida ‐ Miami Cancer Institute
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2011 - 2011 Research Assistant, Memorial Sloan Kettering Cancer Center ‐ Department of Radiation Oncology
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2009 - 2009 Research Fellow, Childrens Hospital Los Angeles ‐ Department of Radiology and Department of Hematology/Oncology
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2007 - 2008 Research Fellow, Cincinnati Children’s Hospital Medical Center ‐ Department of Neurology
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2005 - 2008 Professorial Assistantship and Research Assistant, Michigan State University ‐ Michigan State University
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2007 - 2007 Research Assistant, University of Michigan - Ann Arbor ‐ W.K. Kellogg Eye Center
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Disciplines

Research Interests

Grants

2021 - 2032 Study of LUNG Stereotactic Ablative Adaptive Radiotherapy (LUNG STAAR)
Baptist Health South Florida, Viewray, Inc. - NCT04917224; 2020-KOT-005
Role: Principal Investigator
2020 - 2030 A Phase II/III Randomized, Open-Label Study of Toca 511, A Retroviral Replicating Vector, Combined with Toca FC with Temozolomide and Radiation Followed by Adjuvant Temozolomide and Toca FC Compared to Temozolomide and Radiation Followed by Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma
RTOG Foundation Study - NCT04105374; NRG BN006
Role: Radiation Oncology Study Chair
2017 - 2030 A Phase II Randomized Trial of Proton Vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas
NRG Oncology - NCT03180502
Role: Institutional Principal Investigator
2020 - 2028 A Multicenter Observational Study of GammaTile™ Surgically Targeted Radiation Therapy (STaRT) in Intracranial Brain Neoplasms
GT Medical Technologies, Inc. - NCT04427384; GTM-101
Role: Principal Investigator
2017 - 2027 Maintenance Systemic Therapy Versus Local Consolidative Therapy (LCT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial
NRG Oncology - NCT03137771
Role: Institutional Principal Investigator
2015 - 2027 Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer
NRG Oncology - NCT02635009; NRG CC003
Role: Institutional Principal Investigator
2020 - 2026 Dose-Escalated Spine SbRT (DESSRT) Trial for Localized Metastasis to the Spinal Column
Baptist Health Florida Foundation - NCT04802603; 2020-KOT-003
Role: Principal Investigator
2019 - 2026 Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab
National Cancer Institute (NCI), NRG Oncology - NCT03811002
Role: Institutional Principal Investigator
2014 - 2026 Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation with Concomitant and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma
NRG Oncology, National Cancer Institute (NCI), Radiation Therapy Oncology Group - NCT02179086
Role: Institutional Principal Investigator
2021 - 2025 A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on The Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma
National Cancer Institute (NCI) - NCT04729959; NRG BN010
Role: Radiation Oncology Study Chair
2021 - 2024 A Feasibility Study of Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) in One Fraction for Inoperable Primary or Metastatic Carcinoma (SMART ONE)
Baptist Health Florida, Viewray, Inc. - NCT04939246
Role: Co-Investigator
2020 - 2024 Randomized Phase II Study of Radiation Therapy Alone Versus Radiation Therapy Plus
Medtronic - NCT04375891; 2018-KOT-001
Role: Principal Investigator
2019 - 2023 Durvalumab with Thoracic Radiation Therapy without Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer (DART)
Memorial Sloan Kettering Cancer Center - NCT03999710; MSK 19-218
Role: Institutional Principal Investigator
2016 - 2023 LUNAR: Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields) Concurrent with Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure.
NovoCure, LTD - NCT02973789; EF-24
Role: Institutional Principal Investigator
2021 - 2022 Characterization of Large Brain Metastases with 18F-Fluciclovine PET/CT Treated with Staged Stereotactic Radiosurgery
Baptist Health Florida, Blue Earth Diagnostics - NCT04689048; 2019-KOT-001
Role: Principal Investigator
2019 - 2022 PROMISE-005: A Phase II Randomized Study Assessing the Efficacy of Stereotactic Body Radiotherapy (SBRT) in Patients with Oligometastatic Breast or Lung Cancer
Memorial Sloan Kettering Cancer Center - NCT03808337; MSK 18-486
Role: Institutional Principal Investigator
2018 - 2022 A Randomized Trial of Early, Upfront Palliative Radiation Therapy Versus Standard of Care for Patients with Highest Risk Asymptomatic or Minimally Symptomatic Bone Metastases
Memorial Sloan Kettering Cancer Center - NCT03523351; MSK 18-196
Role: Institutional Principal Investigator
2018 - 2022 A Study of Olaparib and Low Dose Radiotherapy for Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center - NCT03532880; MSK 18-195
Role: Institutional Principal Investigator
2018 - 2021 Phase 1 Trial of Osimertinib with Stereotactic Radiosurgery (SRS) in Patients With Brain Metastases From EGFR Positive Non-Small-Cell Lung Cancer (NSCLC)
Case Comprehensive Cancer Center - NCT03535363
Role: Institutional Principal Investigator
2018 - 2020 Endoesophageal brachytherapy for patients with esophageal cancer: A balloon repositioning, multichannel radiation applicator for optimizing treatment delivery
Case Comprehensive Cancer Center - NCT03335813; CASE5217
Role: Co-Investigator
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Professional Service and Affiliations

2020 - Present Member, Radiation Safety Committee, Baptist Health South Florida
2020 - Present Committee Moderator, Committee Member, Viewray Inc. Research Consortium (CNS)
2019 - Present Co-organizer. Glioblastoma / Brain Metastasis Clinical Working Group, National Cancer Institute
2018 - Present Course Director, Annual Miami Brain Symposium
2017 - Present Member. Data Safety and Monitoring Committee, Miami Cancer Institute, Baptist Health South Florida
2017 - 2022 Co-Chair. Committee Member. CNS Committee, Proton Collaborative Group
2021 - 2021 Course Director, Miami Radiosurgery Conference
2019 - 2021 Course Director, Introduction of Gamma Knife Radiosurgery Training Course
2010 - 2011 Public Relations and Editor. Medical Student Research Journal, Michigan State University College of Human Medicine, East Lansing, MI
Advisory Board Member, Brain Cancer Faculty
Editorial Board, Frontiers in Oncology
Editorial Contributor, PracticeUpdate’s Center of Excellence, Elsevier, Inc.
Associate Editor, Radiation Oncology
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Honors and Awards

  • 2017 Cleveland Clinic Educational Foundation Excellence in Teaching Award
  • 2016 Cleveland Clinic Educational Foundation Excellence in Teaching Award
  • 2015 ASTRO Annual Meeting Resident Abstract Award (2nd place clinical)
  • 2014-2015 The Cleveland Clinic Jerrold P. Saxton Award for Clinical Excellence
  • 2011 Inducted into the Alpha Omega Alpha Honors Medical Society
  • 2011, 2012 Wilbur C. Wright Memorial Scholarship
  • 2008-2011 The Bernard F. and Melissa Anne Bailey Family Scholarship Award
  • 2010 Graduate Student Research Enhancement Award
  • 2010 Helen and Verne Beilfuss Memorial Research Award for Cancer-related Research
  • 2008 The Midland County Medical Society Alliance Health Careers Scholarship Award
  • 2008 Stephen D. Redman M.D. Memorial Scholarship Award
  • 2008 MSU Board of Trustee’s Award for highest cumulative grade point, 4.0
  • 2008 MSU Department of Physiology Award for Academic Excellence
  • 2005-2008 MSU College of Natural Science Dean’s Honor List
  • 2005 Alumni Distinguished Scholars Semi-Finalist
  • 2005 National Merit Finalist
  • 2005 Covenant HealthCare Foundation Scholarship Award
  • 2004 Bausch & Lomb Honorary Science Award, University of Rochester

Education

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July 2012 - June 2017 Residency Program - Radiation Oncology, Cleveland Clinic Foundation
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August 2008 - May 2012 Doctor of Medicine, M.D., Michigan State University ‐ College of Human Medicine
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August 2005 - May 2008 Medical Scholars Program, Michigan State University ‐ College of Human Medicine
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August 2005 - May 2008 Physiology, B.S., Michigan State University ‐ Honors College
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Links

Contact Information

Miami Cancer Institute
8900 N. Kendall Drive
Miami, FL 33176
(786) 596-2000

Articles (155)