Since genes are increasingly seen as determinants of health, we are faced with decisions about whether, or how to alter them in order to ensure that people are healthy, and able to participate in society. Our ideas about what makes a person "normal" in terms of health play a pivotal role in these decisions. Within policy discussions, it is crucial to recognize that genetic testing and intervention have the potential to further stigmatize and devalue the disabled on the basis of variations and differences in our bodies.