Pneumonia and diarrhea can be addressed with early detection and education, yet low rates of literacy and high rates of poverty impact the ability of parents in rural Guatemala to recognize and seek treatment for their children. This article describes the health promotion program implemented to address these and other common health problems in one isolated community. A promotora program utilizes informal, indigenous leaders within the community to promote health in Latino populations. Developing a health education program based on the promotora concept empowered the women of the community by giving them the knowledge and skills to improve the health of their families and their community. The lessons learned from this culturally-based health promotion model are appropriate for application in local and international communities.