This chapter examines the socioeconomic, historical, and cultural context of the United Republic of Tanzania and how it has shaped the country’s family life and family life education throughout the precolonial, colonial, and postcolonial eras. The context includes social factors such as changes in family structures and functions, emergence of HIV/AIDS, sexuality and family life education programs, and related family and health policies. Utilizing the socio-ecological perspective, the article delineates family strengths, gaps, and opportunities available to key stakeholders to meet the contemporary family life education needs for the Tanzanian families.