Generation Z (Gen Z) is the second largest living generation in the United States, totaling about 69 million. According to recently released research by the Barna Group, this generation includes individuals born between 1999 and 2015, whose worldview is shaped by six major trends. These include: (1) they are “screenagers;” (2) their worldview is post-Christian; (3) “safe spaces” are normal; (4) real safety is a myth; (5) they are diverse; and (6) their parents are double-minded. Considering these six core trends, how can we effectively preach to Generation Z? Drawing on data from a recent survey, this paper will provide an overview of effective preaching techniques that will not only connect with Gen Z but will also assist them in living as faithful and committed disciples in a post-Christian culture.