Coordinated Regulation of Apoptosis and Cell Proliferation by Transforming Growth ß1 in Cultured Uterine Epithelial CellsProceedings of the National Academy of Sciences
PubMed Central® IDPMC51457
AbstractCell and tissue growth is regulated through a complex interplay of stimulatory and inhibitory signals. We describe two biological actions of transforming growth factor beta 1 (TGF-beta 1) in primary cultures of rabbit uterine epithelial cells: (i) inhibition of cell proliferation and (ii) a concomitant increase in cells undergoing apoptosis (programmed cell death). It is proposed that proliferation and apoptosis together comprise normal cell growth regulation.
Citation InformationRocco J. Rotello, Rita C. Lieberman, Anthony F. Purchio and Lazaro E. Gerschenson. "Coordinated Regulation of Apoptosis and Cell Proliferation by Transforming Growth ß1 in Cultured Uterine Epithelial Cells" Proceedings of the National Academy of Sciences Vol. 88 Iss. 8 (1991) p. 3412 - 3415
Available at: http://works.bepress.com/rocco_rotello/33/