Due to the biological and industrial importance of hypochlorous acid, the development of optical probes for HOCl has been an active research area. Hypochlorous acid and hypochlorite can oxidize electron-rich analytes with accompanying changes in molecular sensor spectroscopic profiles. Probes for such processes may monitor HOCl levels in the environment or in an organism and via bio-labeling or bioimaging techniques. This review summarizes recent developments in the area of chromogenic and fluorogenic chemosensors for HOCl.
Recent Progress in Chromogenic and Fluorogenic Chemosensors for Hypochlorous AcidAnalyst
SponsorThe work was supported by the National Natural Science Foundation of China (No. 21102086, 21472118), the Shanxi Province Science Foundation for Youths (No. 2012021009-4, 2013011011-1), the Shanxi Province Foundation for Returnee (No. 2012-007), the Taiyuan Technology Star Special (No. 12024703), the Program for the Top Young and Middle-aged Innovative Talents of Higher Learning Institutions of Shanxi (2013802), Talents Support Program of Shanxi Province (2014401), the CAS Key Laboratory of Analytical Chemistry for Living Biosystems Open Foundation (ACL201304) and the National Institutes of Health (R15EB016870).
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Citation InformationYue, Y., Huo, F., Yin, C., Escobedo, J. O., & Strongin, R. M. (2016). Recent progress in chromogenic and fluorogenic chemosensors for hypochlorous acid. Analyst, 141(6), 1859-1873.