Article
A Seminaphthofluorescein-Based Fluorescent Chemodosimeter for the Highly Selective Detection of Cysteine
Chemistry Faculty Publications and Presentations
Sponsor
This work was support by the National Institutes of Health (RO1 EB002044)
Document Type
Post-Print
Publication Date
1-1-2012
Subjects
- Cysteine -- Detection,
- Fluorescent probes,
- Dosimeters -- Applications to biochemistry
Disciplines
Abstract
A fluorescent chemodosimeter for cysteine detection was developed based on a tandem conjugate addition and intramolecular cyclization reaction. The method exhibited an excellent selectivity for cysteine over other biothiols such as homocysteine and glutathione.
DOI
10.1039/C2OB25178G
Persistent Identifier
http://archives.pdx.edu/ds/psu/11116
Citation Information
Xiaofeng Yang, Yixing Guo and Robert M. Strongin. "A Seminaphthofluorescein-Based Fluorescent Chemodosimeter for the Highly Selective Detection of Cysteine" (2012) Available at: http://works.bepress.com/robert_strongin/2/
This is the author’s version of a work that was accepted for publication in Organic & Biomolecular Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections,structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Organic & Biomolecular Chemistry, (2012), 10(14): 2739–2741 and can be found online at: http://dx.doi.org/10.1039/C2OB25178G
Reproduced by permission of The Royal Society of Chemistry (RSC)