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An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells
Australian Institute for Innovative Materials - Papers
  • Robert Burger, Dublin City University
  • D Kurzbuch, Dublin City University
  • Robert Gorkin III, University of Wollongong
  • Gregor Kijanka
  • Macdara Glynn
  • C Mcdonagh, Dublin City University
  • Jens Ducree, Dublin City University
RIS ID
95736
Publication Date
1-1-2015
Publication Details

Burger, R., Kurzbuch, D., Gorkin, R., Kijanka, G., Glynn, M., McDonagh, C. & Ducree, J. (2015). An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells. Lab on a Chip: miniaturisation for chemistry, physics, biology, materials science and bioengineering, 15 (2), 378-381.

Abstract

In this work we present a centrifugal microfluidic system enabling highly efficient collective trapping and alignment of particles such as microbeads and cells, their multi-colour fluorescent detection and subsequent manipulation by optical tweezers. We demonstrate array-based capture and imaging followed by "cherry-picking" of individual particles, first for fluorescently labelled polystyrene (PS) beads and then for cells. Different cell lines are discriminated based on intracellular as well as surface-based markers.

Citation Information
Robert Burger, D Kurzbuch, Robert Gorkin III, Gregor Kijanka, et al.. "An integrated centrifugo-opto-microfluidic platform for arraying, analysis, identification and manipulation of individual cells" (2015) p. 378 - 381
Available at: http://works.bepress.com/robert_gorkin/12/