Skip to main content
Article
A community-wide perspective of secular trends in the therapeutic management of patients with acute myocardial infarction. The Worcester Heart Attack Study
Quantitative Health Sciences Publications and Presentations
  • Robert J. Goldberg, University of Massachusetts Medical School
UMMS Affiliation
Department of Medicine, Division of Cardiovascular Medicine
Publication Date
1-1-1989
Document Type
Article
Subjects
Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Cohort Studies; Digoxin; Female; Humans; Longitudinal Studies; Male; Massachusetts; Middle Aged; Myocardial Infarction; Nitrates; Physician's Practice Patterns; Platelet Aggregation Inhibitors; Time Factors
Abstract
As part of an ongoing community-wide study of time trends in the incidence and case-fatality rates of patients hospitalized with acute myocardial infarction (MI) in 16 Worcester, Mass., metropolitan hospitals during the calendar years 1975, 1978, 1981, and 1984, changes over time in the therapeutic management of 3,263 patients with validated acute MI were examined. Beta-blocker and nitrate therapy use increased consistently and dramatically. Use of antiplatelet agents was inconsistent, while use of digoxin remained stable. Use of antiarrhythmic medications other than lidocaine decreased consistently while lidocaine use increased between 1975 and 1978 and then leveled off to being used in approximately 45% of hospitalized patients with acute MI in 1981 and 1984. A variety of demographic (e.g. age, sex, teaching hospital) and clinical characteristics (e.g. MI order, MI type, MI location, peak CPK findings, occurrence of acute clinical complications) were also associated with the use of these therapies. The results of this community-wide study suggest changes over time in the therapeutic management of patients hospitalized with acute MI and of various patient demographic and clinical factors associated with the use of these agents.
Rights and Permissions
Citation: Cardiology. 1989;76(2):105-11.
Related Resources
Link to Article in PubMed
Citation Information
Robert J. Goldberg. "A community-wide perspective of secular trends in the therapeutic management of patients with acute myocardial infarction. The Worcester Heart Attack Study" Vol. 76 Iss. 2 (1989) ISSN: 0008-6312 (Linking)
Available at: http://works.bepress.com/robert_goldberg/184/