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Article
Focused and Deep Brain Magnetic Stimulation Using New Coil Design in Mice
International IEEE/EMBS Conference on Neural Engineering
  • S. D. March, Iowa State University
  • S. McAtee, Iowa State University
  • M. Senter, Iowa State University
  • K. Spoth, Iowa State University
  • Daniel R. Stiner, Iowa State University
  • Lawrence J. Crowther, Iowa State University
  • Ravi L. Hadimani, Iowa State University
  • David C. Jiles, Iowa State University
Document Type
Conference Proceeding
Conference
IEEE EMBS Conference on Neural Engineering
Publication Version
Accepted Manuscript
Link to Published Version
http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6695887
Publication Date
1-1-2013
DOI
10.1109/NER.2013.6695887
Conference Title
6th Annual International IEEE EMBS Conference on Neural Engineering
Conference Date
November 6-8, 2013
Geolocation
(32.715738, -117.16108380000003)
Abstract

Deep brain transcranial magnetic stimulation (TMS) offers promising treatment for neurological disorders that originate from deeper regions of the brain, such as Parkinson's disease. Coils designed for the human head need significant redesigning to stimulate selective regions of the mouse brain for advanced TMS therapy analysis. We report a focused and deep brain TMS coil for mice that is based on a two coil configuration similar to the 'Halo coil'. A heterogeneous MRI derived head model of mouse was used to obtain an electric field of about 150 V/m in selective deeper regions of the brain. Focality of stimulation was quantified using the ratio of half value volume to half value of depth of electric field. A prototype of the final coil design was fabricated and characterized to compare simulated and physical magnetic field profiles.

Comments

Copyright 2013 IEEE. This is a manuscript of an article from 6th Annual International IEEE EMBS Conference on Neural Engineering San Diego, California, 6 - 8 November, 2013: 6695887, doi: 10.1109/NER.2013.6695887. Posted with permission.

Copyright Owner
IEEE
Language
en
File Format
application/pdf
Citation Information
S. D. March, S. McAtee, M. Senter, K. Spoth, et al.. "Focused and Deep Brain Magnetic Stimulation Using New Coil Design in Mice" San Diego, CaliforniaInternational IEEE/EMBS Conference on Neural Engineering Iss. 6695887 (2013) p. 125 - 128
Available at: http://works.bepress.com/rlhadimani/17/