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Prototyping Nanorod Control: A DNA Double Helix Sheathed within a DNA Six-Helix Bundle
Cell Chemistry Biology
  • Risheng Wang, Missouri University of Science and Technology
  • Wenyan Liu
  • Nadrian C. Seeman

The control of the structure of matter is a key goal of nanoscience. DNA is an exciting molecule for control because it forms programmable intermolecular interactions. Stiff DNA structures, such as the double crossover motif, the tensegrity triangle, and the six-helix bundle (6HB) have been used to produce periodic arrays of DNA components. the 6HB motif consists of six DNA double helices flanking an inner cavity whose diameter is similar to that of a double helix. This motif appears to be an excellent candidate to sheathe and control nanorods by inserting them into the cavity, and then to control the placement and orientation of the rod by controlling the DNA sheath. Here, we prototype this kind of control by using a seventh DNA double helix as the nanorod and fixing it inside the 6HB motif.

Keywords and Phrases
  • DNA,
  • Hydroxyl Radical,
  • Nanotube,
  • Atomic Force Microscopy,
  • Chemistry,
  • Metabolism,
  • Molecular Genetics,
  • Nucleotide Sequence,
  • Ultrastructure,
  • Molecular Sequence Data
Document Type
Article - Journal
Document Version
File Type
© 2009 Elsevier, All rights reserved.
Publication Date
Citation Information
Risheng Wang, Wenyan Liu and Nadrian C. Seeman. "Prototyping Nanorod Control: A DNA Double Helix Sheathed within a DNA Six-Helix Bundle" Cell Chemistry Biology Vol. 16 Iss. 8 (2009) p. 862 - 867 ISSN: 1074-5521
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