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Article
Metal-Ion Responsive Reversible Assembly of DNA Origami Dimers: G-Quadruplex Induced Intermolecular Interaction
Nanoscale
  • Shuo Yang
  • Wenyan Liu, Missouri University of Science and Technology
  • Rachel Nixon
  • Risheng Wang, Missouri University of Science and Technology
Abstract

We present a novel metal-ion stimulated organization of DNA origami nanostructures by employing G-quadruplexes as stimuli-responsive bridges. The reversible assembly process of DNA origami was the result of conformational changes between the G-quadruplex and its single-strand state induced by monovalent cations. This study might stimulate a new design of responsive DNA-based intelligent nanomaterials.

Department(s)
Chemistry
Second Department
Mechanical and Aerospace Engineering
Comments
This work is supported by University of Missouri Research Board, Material Research Center at Missouri University of Science and Technology and College of arts and Science of Missouri S&T.
Keywords and Phrases
  • Assembly process,
  • Conformational change,
  • DNA origamis,
  • G-quadruplexes,
  • Intermolecular interactions,
  • Monovalent cations,
  • Stimuli-responsiv
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2018 Royal Society of Chemistry, All rights reserved.
Publication Date
2-1-2018
Publication Date
01 Feb 2018
Disciplines
Citation Information
Shuo Yang, Wenyan Liu, Rachel Nixon and Risheng Wang. "Metal-Ion Responsive Reversible Assembly of DNA Origami Dimers: G-Quadruplex Induced Intermolecular Interaction" Nanoscale Vol. 10 Iss. 8 (2018) p. 3626 - 3630 ISSN: 2040-3364
Available at: http://works.bepress.com/risheng-wang/22/