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Article
Blunt-Ended DNA Stacking Interactions in a 3-Helix Motif
Chemical Communications
  • Risheng Wang, Missouri University of Science and Technology
  • Akinori Kuzuya
  • Wenyan Liu
  • Nadrian C. Seeman
Abstract

We demonstrate that intermolecular stacking is capable of forming one-dimensional arrays of a blunt-ended 3-helix DNA motif. the array can be visualized in the atomic force microscopy through conjugated streptavidin nanoparticles. We estimate the strength of the triple stacking interaction to be -8.6 kcal mol-1.

Department(s)
Chemistry
Keywords and Phrases
  • DNA,
  • Nanoparticle,
  • Streptavidin,
  • Atomic Force Microscopy,
  • DNA Determination,
  • DNA Structure,
  • Molecular Interaction,
  • Chemistry,
  • Conformation,
  • Nucleotide Sequence,
  • Thermodynamics,
  • Base Sequence,
  • Nucleic Acid Conformation
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2010 Royal Society of Chemistry, All rights reserved.
Publication Date
6-1-2010
PubMed ID
20532374
Disciplines
Citation Information
Risheng Wang, Akinori Kuzuya, Wenyan Liu and Nadrian C. Seeman. "Blunt-Ended DNA Stacking Interactions in a 3-Helix Motif" Chemical Communications Vol. 46 Iss. 27 (2010) p. 4905 - 4907 ISSN: 1359-7345
Available at: http://works.bepress.com/risheng-wang/2/