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Article
Control of DNA Origami Inter-Tile Connection with Vertical Linkers
Chemical Communications
  • Risheng Wang, Missouri University of Science and Technology
  • Kent Gorday
  • Colin Nuckolls
  • Shalom J. Wind
Abstract

This communication describes a new method that enables high yield assembly along both of the two-dimensional edges of DNA origami tiles by controlling the Mg2+ concentration; high Mg2+ concentrations promote linkage connections between the vertical edges of the tiles. As a demonstration, DNA origami dimers assembled from two rectangular origami along the vertical edges are used as scaffolds for the double sided assembly of gold nanoparticles with different inter-particle spacings.

Department(s)
Chemistry
Keywords and Phrases
  • DNA,
  • Gold,
  • Magnesium,
  • Metal Nanoparticles,
  • Microscopy, Atomic Force
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2016 Royal Society of Chemistry, All rights reserved.
Publication Date
11-1-2016
PubMed ID
26662034
Disciplines
Citation Information
Risheng Wang, Kent Gorday, Colin Nuckolls and Shalom J. Wind. "Control of DNA Origami Inter-Tile Connection with Vertical Linkers" Chemical Communications Vol. 52 Iss. 8 (2016) p. 1610 - 1613 ISSN: 1359-7345
Available at: http://works.bepress.com/risheng-wang/19/