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Article
Cost Effective Surface Functionalization of Gold Nanoparticles with a Mixed DNA and PEG Monolayer for Nanotechnology Applications
RSC Advances
  • Risheng Wang, Missouri University of Science and Technology
  • Isabella Bowling
  • Wenyan Liu, Missouri University of Science and Technology
Abstract

A cost effective and generally applicable co-functionalization of gold nanoparticles with a mixed DNA and PEG polymers is reported. Compared to the pure DNA functionalization method, this protocol uses a much smaller amount of thiol-DNA to achieve a similar binding efficacy of gold nanoparticles with DNA origami nanostructures. The lower consumption of DNA provides a scaling-up potential for the application of DNA-nanoparticle conjugates in nanotechnology.

Department(s)
Chemistry
Keywords and Phrases
  • Cost Effectiveness,
  • Fiber Optic Sensors,
  • Gold,
  • Metal Nanoparticles,
  • Nanoparticles,
  • Nanostructures,
  • Nanotechnology,
  • Binding Efficacy,
  • Dna Nanoparticles,
  • Dna Origamis,
  • Functionalizations,
  • Surface Functionalization
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2017 Royal Society of Chemistry, All rights reserved.
Publication Date
1-1-2017
Publication Date
01 Jan 2017
Disciplines
Citation Information
Risheng Wang, Isabella Bowling and Wenyan Liu. "Cost Effective Surface Functionalization of Gold Nanoparticles with a Mixed DNA and PEG Monolayer for Nanotechnology Applications" RSC Advances Vol. 2017 Iss. 7 (2017) p. 3676 - 3679 ISSN: 2046-2069
Available at: http://works.bepress.com/risheng-wang/16/