This essay traces the history of the law of police interrogation in the United States, emphasizing that this body of law is largely a product of United States Supreme Court cases interpreting the United States Constitution. The essay reviews the three sections of the Constitution that regulate interrogation practices: the Fifth Amendment, the Due Process Clause of the Fifth and Fourteenth Amendments, and the Sixth Amendment. The essay also explores the Court’s major interrogation-related decisions under each of these constitutional provisions.