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Article
Use of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 (COX-2) inhibitors: Indications and complications
Journal of the American Osteopathic Association
  • Richard A. Pascucci, Philadelphia College of Osteopathic Medicine
Document Type
Article
Publication Date
1-1-2002
Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medications-both prescription and over the counter-in the United States. Gastrointestinal side effects from NSAIDs are responsible for significant patient morbidity and mortality as well as healthcare cost. With the development of cyclooxygenase-2 (COX-2) specific inhibitors, these serious adverse reactions have been significantly reduced without affecting therapeutic benefit; however, the need for careful monitoring of patients on therapy with traditional NSAIDs and COX-2 inhibitors continues. In this article, recent developments regarding COX-2 inhibitors and potential future uses of this class of drugs are also discussed.

Comments

This article was published in Journal of the American Osteopathic Association, Volume 102, Issue 9, Pages 487-489.

The published version is available at https://jaoa.org/article.aspx?articleid=2092657.

Copyright © 2002.

Citation Information
Richard A. Pascucci. "Use of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 (COX-2) inhibitors: Indications and complications" Journal of the American Osteopathic Association Vol. 102 Iss. 9 (2002) p. 487 - 489
Available at: http://works.bepress.com/richard_pascucci/3/