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Article
Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection
Protein & Peptide Letters
  • V. Vanek, Academy of Sciences of the Czech Republic
  • J. Picha, Academy of Sciences of the Czech Republic
  • M. Budesinsky, Academy of Sciences of the Czech Republic
  • M. Sanda, Academy of Sciences of the Czech Republic
  • J. Jiracek, Academy of Sciences of the Czech Republic
  • Richard C. Holz, Marquette University
  • J. Hlavacek, Academy of Sciences of the Czech Republic
Document Type
Article
Publication Date
1-1-2010
Disciplines
Abstract
The search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,Ldiaminopimelic acid desuccinylase (DapE) has stimulated a development of methodology for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing the different carboxyl groups or lipophilic moieties on their amino group.
Comments

Protein & Peptide Letters. Vol. 17, No. 3 (2010): 405-409. DOI.

Richard C. Holz was affiliated with Loyola University-Chicago at the time of publication.

Citation Information
V. Vanek, J. Picha, M. Budesinsky, M. Sanda, et al.. "Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection" Protein & Peptide Letters (2010) ISSN: 0929-8665
Available at: http://works.bepress.com/richard_holz/1/