Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective ProtectionProtein & Peptide Letters
AbstractThe search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,Ldiaminopimelic acid desuccinylase (DapE) has stimulated a development of methodology for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing the different carboxyl groups or lipophilic moieties on their amino group.
Citation InformationV. Vanek, J. Picha, M. Budesinsky, M. Sanda, et al.. "Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection" Protein & Peptide Letters (2010) ISSN: 0929-8665
Available at: http://works.bepress.com/richard_holz/1/