Article
Metal Redistribution in Largemouth Bass (Micropterus salmoides) in Response to Restrainment Stress and Dietary Cadmium: Role of Metallothionein and Other Metal-Binding Proteins
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology
Document Type
Article
Publication Date
2-1-1992
Keywords
- Cadmium/administration & dosage,
- Bass/metabolism,
- Animals,
- Cadmium/pharmacology,
- Copper/metabolism,
- Stress,
- Zinc,
- Hydrocortisone,
- Intestines,
- Muscles,
- Ovary,
- Tissue Distribution
Abstract
1. Fish stressed by restrainment displayed elevated serum cortisol, copper and zinc levels; dietary cadmium had no effect.
2. Stress/dietary cadmium increased liver copper levels in a metal pool containing metallothionein and non-metallothionein proteins but decreased intestinal zinc bound as low molecular weight forms.
3. After restrainment, zinc losses occurred in dorsal skeletal muscle, ovary and spleen: copper decreased in intestine and pyloric caecum.
4. Dietary cadmium altered intestinal zinc distribution and raised hepatic Cu-binding protein levels but did not alter plasma zinc, copper or cortisol levels.
5. Alterations in zinc and copper concentrations during stress contrast with mammalian models.
DOI
10.1016/0742-8413(92)90270-H
Additional Comments
Grant Support
Disciplines
Citation Information
Daniel N. Weber, Sara Eisch, Richard E. Spieler and David H. Petering. "Metal Redistribution in Largemouth Bass (Micropterus salmoides) in Response to Restrainment Stress and Dietary Cadmium: Role of Metallothionein and Other Metal-Binding Proteins" Comparative Biochemistry and Physiology Part C: Comparative Pharmacology Vol. 101 Iss. 2 (1992) p. 255 - 262 ISSN: 0306-4492 Available at: http://works.bepress.com/richard-spieler/92/
©1992 Published by Elsevier Inc.