This study seeks to understand the perceptions of professors using social media (also called Web 2.0 tools) in the classroom, what kinds of mobile devices are used to access the social media used, and what drives individuals to use them. In addition, it seeks to identify the advantages and concerns faculty has with the use of social media for classroom instruction. Two-Way Multivariate Analysis of Variance (MANOVA) procedure was used to ascertain whether differences existed between two dependent variables and (a) gender, (b) different academic ranks, and (c) gender *rank to determine if there are any interaction effects between genders regarding the magnitude of their perceptions of advantages and concerns about social media uses for classroom instruction as they migrate through the ranks. Professors, regardless of sex or rank, held statistically the same views of the advantages as well as the concerns related to social media usage in the classroom