Building upon previous internship work at the Institute of Mediterranean Studies – Foundation for Research and Technology Hellas (IMS-FORTH), this poster presents a methodology for identifying, mapping, and spatially analyzing changing settlement patterns. Road atlases, historic archival records, and remotely sensed imagery are synthesized to create a preliminary GIS, then archaeological fieldwork targets individual features within a settlement to gather GPS points and establish dates. A second round of digitization results in a highly detailed GIS that records the changing landscape of human settlement in the region. The final step, spatial analysis, tests for significant relationships at both the intra- and inter-settlement scales.