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Article
A Study of Effects of Tissue Inhomogeneity on HIFU Beam
Center for Nondestructive Evaluation Conference Papers, Posters and Presentations
  • Viren R. Amin, Iowa State University
  • Ronald A. Roberts, Iowa State University
  • Tao Long, Iowa State University
  • R. Bruce Thompson, Iowa State University
  • Timothy Ryken, University of Iowa
Document Type
Conference Proceeding
Conference
5th International Symposium on Therapeutic Ultrasound
Publication Date
10-1-2005
Geolocation
(42.3584308, -71.0597732)
Abstract

The potential of high‐intensity focused ultrasound (HIFU) will not be realized unless the effects of overlaying tissues are understood in such a way that allows for estimation of HIFU dose distribution at a target tissue. We employ computational models to examine the impact of phase aberration on tissue ablation. Thompson and Roberts have recently studied the effects of phase aberration on ultrasound focusing in aerospace engine materials such as titanium alloy, and have developed a computational model to examine these effects. The ultrasound beam observed after transmission through the fused quartz (homogeneous) and that observed after transmission through the titanium (inhomogeneous) demonstrate the severe beam wavefield amplitude distortion introduced by the velocity inhomogeneity‐induced phase aberration. We study applicability of this approach to model phase aberration in inhomogeneous tissues and its effect on HIFU dose distribution around the focus. It is hypothesized that the ill‐effects of phase aberration accumulate during propagation through intervening tissue in which field intensities are substantially lower than that in the focal zone, and it is therefore appropriate to use a linear acoustic model to describe the transport of energy from the transducer to the volume targeted for ablation. We present initial results of the simulation and experiments of beam measurements under water without and with different tissue layers. © 2006 American Institute of Physics

Comments

Copyright 2006 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

The following article appeared in AIP Conference Proceedings 829 (2006): 201–205 and may be found at http://dx.doi.org/10.1063/1.2205466.

Copyright Owner
American Institute of Physics
Language
en
Citation Information
Viren R. Amin, Ronald A. Roberts, Tao Long, R. Bruce Thompson, et al.. "A Study of Effects of Tissue Inhomogeneity on HIFU Beam" Boston, MA(2005)
Available at: http://works.bepress.com/rbruce_thompson/17/