The need to address the scarcity of task-specific annotated data has resulted in concerted efforts in recent years for specific settings such as zero-shot learning (ZSL) and domain generalization (DG), to separately address the issues of semantic shift and domain shift, respectively. However, real-world applications often do not have constrained settings and necessitate handling unseen classes in unseen domains – a setting called Zero-shot Domain Generalization, which presents the issues of domain and semantic shifts simultaneously. In this work, we propose a novel approach that learns domain-agnostic structured latent embeddings by projecting images from different domains as well as class-specific semantic text-based representations to a common latent space. In particular, our method jointly strives for the following objectives: (i) aligning the multimodal cues from visual and text-based semantic concepts; (ii) partitioning the common latent space according to the domain-agnostic class-level semantic concepts; and (iii) learning a domain invariance w.r.t. the visual-semantic joint distribution for generalizing to unseen classes in unseen domains. Our experiments on the challenging DomainNet and DomainNet-LS benchmarks show the superiority of our approach over existing methods, with significant gains on difficult domains like quickdraw and sketch. © 2021, CC BY.