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Article
Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis
Advances in Bioscience and Biotechnology
  • Mula Ramanjaneya, Philadelphia College of Osteopathic Medicine
  • Rangaiah Shashidharamurthy, Philadelphia College of Osteopathic Medicine
Document Type
Article
Publication Date
1-1-2013
Abstract
Tumor necrosis factor alpha (TNF-α) a cytokine has been shown to be the key player during the pathogenesis of several autoimmune inflammatory disorders (presumably sterile inflammation) including rheumatoid arthritis (RA). Several studies have shown that TNF-α is mainly involved in the proinflammatory responses. However recent studies have reported multifunctional role of TNF-α during the development of RA. Therefore, in this article we have highlighted the distinct functions of TNF-α during pathogenesis of RA
Comments
This article was published in Advances in Bioscience and Biotechnology, Volume 4, Number 10, 2013.
The published version is available at http://dx.doi.org/10.4236/abb.2013.410123
Copyright 2013 ©Ramanjaneya and Shashidharamurthy
Citation Information
Mula Ramanjaneya and Rangaiah Shashidharamurthy. "Multifacted Role of TNF-α During the Pathogenesis of Rheumatoid Arthritis" Advances in Bioscience and Biotechnology Vol. 4 Iss. 10 (2013) p. 937 - 940
Available at: http://works.bepress.com/rangaiah_shashidharamurthy/1/