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A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate
Tetrahedron Letters (2011)
  • Ram S. Mohan, Illinois Wesleyan University
  • Matthew R. Bockman
  • Veronica V. Angeles
  • Julia M. Martino
  • Purav P. Vagadia
Abstract

A mild method for the deprotection of THP ethers catalyzed by iron(III) tosylate (2.0 mol %) in CH3OH has been developed. Iron(III) tosylate, Fe(OTs)3.6H2O, is a commercially available solid that is inexpensive, noncorrosive, and easy to handle. The room temperature reaction conditions make this method attractive for deprotection of a range of THP ethers.

Disciplines
Publication Date
2011
Citation Information
Ram S. Mohan, Matthew R. Bockman, Veronica V. Angeles, Julia M. Martino, et al.. "A mild method for the deprotection of tetrahydropyranyl (THP) ethers catalyzed by iron(III) tosylate" Tetrahedron Letters Vol. 52 (2011)
Available at: http://works.bepress.com/ram_mohan/37/