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An Efficient Method for the Chemoselective Synthesis of Acylals from Aromatic Aldehydes Using Bismuth Triflate
Tetrahedron (2001)
  • Ram S. Mohan, Illinois Wesleyan University
  • Marc D. Carrigan
  • Kyle J. Eash
  • Matthew C. Oswald
Abstract

Aromatic aldehydes are smoothly converted into the corresponding acylals in good yields in the presence of 0.10 mol% Bi(OTf)3•xH2O. Ketones are not affected under the reaction conditions. The highly catalytic nature of bismuth triflate and the fact that it is relatively non-toxic, easy to handle and insensitive to small amounts of air and moisture makes this procedure especially attractive for large-scale synthesis.

Keywords
  • Acylals,
  • acylation,
  • bismuth and compounds,
  • protecting groups.
Disciplines
Publication Date
2001
Citation Information
Ram S. Mohan, Marc D. Carrigan, Kyle J. Eash and Matthew C. Oswald. "An Efficient Method for the Chemoselective Synthesis of Acylals from Aromatic Aldehydes Using Bismuth Triflate" Tetrahedron Vol. 42 (2001)
Available at: http://works.bepress.com/ram_mohan/14/