Bismuth Compounds in Organic Synthesis. Deprotection of Ketoximes Using Bismuth Bromide-Bismuth TriflateTetrahedron Letters (2003)
Ketoximes undergo deprotection in CH3CN/acetone/H2O (3:6:1) in the presence of 20–40 mol% BiBr3/5 mol% Bi(OTf)3. Bismuth(III) salts are relatively non-toxic, insensitive to air and inexpensive. These features coupled with the use of a relatively non-toxic solvent system make this method an attractive alternative to existing routes for deprotection of ketoximes.
- bismuth and compounds; oximes; deprotection; environment-friendly chemistry.
Citation InformationRam S. Mohan, Joshua N. Arnold, Patrick D. Hayes and Robert L. Kohaus. "Bismuth Compounds in Organic Synthesis. Deprotection of Ketoximes Using Bismuth Bromide-Bismuth Triflate" Tetrahedron Letters Vol. 44 (2003)
Available at: http://works.bepress.com/ram_mohan/10/