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Article
Conceptual and Mathematical Models of Batch Simultaneous Saccharification and Fermentation: Dimensionless Groups for Predicting Process Dynamics
Journal of Biological Systems
  • D. Raj Raman, Iowa State University
  • Robert Philip Anex, Iowa State University
Document Type
Article
Publication Date
6-12-2012
DOI
10.1142/S0218339012500064
Abstract

This paper describes a modeling effort demonstrating that dimensionless groupings of classical process parameters can be used to predicting process dynamics of batch simultaneous saccharification and fermentation (SSF) processes. Michaelis–Menten enzyme kinetics and Monod growth kinetics were employed, and inhibition of enzyme action and inhibition of microbial growth were neglected. The SSF process was characterized by the relative durations of three phases: A microbially-limited phase, a hydrolysis-limited phase, and a monosaccharide-depletion phase. The duration of these three phases were interrelated, and well predicted by the dimensionless magnitude of the monosaccharide peak (MSP). Thus, the MSP could be used as a single-value descriptor of an SSF process. The dimensionless ratio of the initial hydrolysis rate to the initial substrate consumption rate was shown to predict MSP, and an overall system time constant was shown to predict the total run time of a batch SSF process.

Comments

Electronic version of an article published as Journal of Biological Systems 20, no. 2 (June 2012): 195–211, doi:10.1142/S0218339012500064. © World Scientific Publishing Company, http://www.worldscientific.com/worldscinet/jbs.

Copyright Owner
World Scientific Publishing Company
Language
en
Date Available
January 7, 2013
File Format
application/pdf
Citation Information
D. Raj Raman and Robert Philip Anex. "Conceptual and Mathematical Models of Batch Simultaneous Saccharification and Fermentation: Dimensionless Groups for Predicting Process Dynamics" Journal of Biological Systems Vol. 20 Iss. 2 (2012) p. 195 - 211
Available at: http://works.bepress.com/raj_raman/5/