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Selected Works of Qijing Zhang
Article
Coupled Phase-Variable Expression and Epitope Masking of Selective Surface Lipoproteins Increase Surface Phenotypic Diversity in Mycoplasma hominis
Infection and Immunity (2001)
  • Qijing Zhang, University of Missouri School of Medicine
  • Kim S. Wise, University of Missouri School of Medicine
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Abstract
A new mechanism expanding mycoplasmal surface diversity is described. Exposure of surface epitopes on a constitutively expressed membrane protein (P56) of Mycoplasma hominis was subject to high-frequency phase variation due to phase-variable expression of the P120 antigen and its selective masking of P56 epitopes. Phase-variable masking may confer previously unrealized adaptive capabilities on mycoplasmas.

Disciplines
Publication Date
August, 2001
DOI
10.1128/IAI.69.8.5177–5181.2001
Publisher Statement
Copyright © 2001, American Society for Microbiology
Citation Information
Qijing Zhang and Kim S. Wise. "Coupled Phase-Variable Expression and Epitope Masking of Selective Surface Lipoproteins Increase Surface Phenotypic Diversity in Mycoplasma hominis" Infection and Immunity Vol. 69 Iss. 8 (2001) p. 5177 - 5181
Available at: http://works.bepress.com/qijing-zhang/69/