Article
Emergence of Extensively Drug-Resistant Proteus mirabilis Harboring a Conjugative NDM-1 Plasmid and a Novel Salmonella Genomic Island 1 Variant, SGI1-Z
Antimicrobial Agents and Chemotherapy
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
10-1-2015
DOI
10.1128/AAC.00292-15
Abstract
Acquisition of blaNDM-1 in bacterial species, such as Proteus mirabilis that is intrinsically resistant to tetracycline, tigecycline and colistin, will make clinical treatment extremely difficult. Here, we characterized an NDM-1-producing clinical isolate of P. mirabilis (PM58) that displayed an extensively drug-resistant (XDR) phenotype, susceptible only to aztreonam. Molecular analysis revealed that PM58 harbored both a conjugative NDM-1 plasmid and a novel Salmonella genomic island 1 variant on chromosome.
Copyright Owner
American Society for Microbiology
Copyright Date
2015
Language
en
File Format
application/pdf
Citation Information
Shangshang Qin, Hui Qi, Qijing Zhang, Di Zhao, et al.. "Emergence of Extensively Drug-Resistant Proteus mirabilis Harboring a Conjugative NDM-1 Plasmid and a Novel Salmonella Genomic Island 1 Variant, SGI1-Z" Antimicrobial Agents and Chemotherapy Vol. 59 Iss. 10 (2015) p. 6601 - 6604 Available at: http://works.bepress.com/qijing-zhang/26/
This article is published as Qin, Shangshang, Hui Qi, Qijing Zhang, Di Zhao, Zhen-Zhen Liu, Hao Tian, Lijuan Xu et al. "Emergence of extensively drug-resistant Proteus mirabilis harboring a conjugative NDM-1 plasmid and a novel Salmonella genomic island 1 variant, SGI1-Z." Antimicrobial agents and chemotherapy 59, no. 10 (2015): 6601-6604. doi: 10.1128/AAC.00292-15. Posted with permission.