Article
Microfluidic gel arrays for the
study of enzymatic activity
Bioengineering
Document Type
Conference Proceeding
Publication Date
10-1-2014
Publisher
International Conference on Miniaturized
Systems for Chemistry and Life Sciences
Disciplines
Abstract
We present a novel and flexible gel array platform to study enzymatic activity in confined environments. Recent research has highlighted the importance of studying proteins in confined environments that replicate the inside of cells rather than studying proteins in dilute solutions. Our platform allows the punctual and selective introduction of substrates and the quantitative readout of product formation to study the effect of protein confinement on enzymatic activity.
Citation Information
Sowash, C.; Smith, C.; Tullis, J.; Kunkel, J.; Asuri, P.; Abbyad, P. Microfluidic gel arrays for the
study of enzymatic activity, Proceedings of MicroTAS Conference, W.249b (2014).