Article
Differential surface stress sensor for detection of chemical and biological species
Applied Physics Letters
Document Type
Article
Disciplines
Publication Date
10-7-2008
DOI
10.1063/1.2996411
Abstract
We report a sensor consisting of two micromachined cantilevers (a sensing/reference pair) that is suitable for detection of chemical and biological species. The sensing strategy involves coating the sensing cantilever with receptors that have high affinities for the analyte. The presence of analyte is detected by determining the differential surface stress associated with its adsorption/absorption to the sensing cantilever. An interferometric technique is utilized to measure the differential bending of the sensing cantilever with respect to reference. Surface stress associated with hybridization of single stranded DNA is measured to demonstrate the unique advantages of the sensor.
Rights
Copyright 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.
Copyright Owner
American Institute of Physics
Copyright Date
2008
Language
en
File Format
application/pdf
Citation Information
K. Kang, Marit Nilsen-Hamilton and Pranav Shrotriya. "Differential surface stress sensor for detection of chemical and biological species" Applied Physics Letters Vol. 93 Iss. 143107 (2008) p. 1 - 3 Available at: http://works.bepress.com/pranav_shrotriya/23/
The following article appeared in Applied Physics Letters 93, 143107 (2008); and may be found at, doi:10.1063/1.2996411.