Dissection of a 98-year-old female cadaver identified three previously unrecorded simultaneous variations in the iliac region. A variant iliacus muscle originated in the iliac fossa and then split at the insertion point of the lesser trochanter to blend with the psoas major and vastus medialis muscles. Two variant psoas muscles were found located medial and lateral to the psoas major muscle. The position of the psoas muscle variations resulted in an altered course of the typical path of both the femoral and obturator nerves. The current findings and clinical significance are discussed.