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Hospital-based Surveillance of Invasive Pneumococcal Disease and Pneumonia in South Bangalore, India.
Indian Pediatr. (2015)
  • R Nisarga
  • R Premalatha
  • Shivananda
  • KL Ravikumar
  • U Shivappa
  • A Gopi
  • SB Chikkadasarahalli
  • R Batuwanthudawe
  • Paul E Kilgore, Wayne State University
  • SA Kim
  • I Balter
  • S Jouve
  • J Ye
  • M Moscariello
Abstract

OBJECTIVE: To estimate the incidence of invasive pneumococcal disease and pneumonia, distribution of pneumococcal serotypes, and antibiotic susceptibility in children aged 28 days to <60 months. DESIGN: Hospital-based surveillance. SETTING: South Bangalore, India. PARTICIPANTS: 9950 children aged 28 days to <60 months with clinical suspicion of invasive pneumococcal disease or pneumonia. RESULTS: The estimated at-risk population included 224,966 children <5 years of age. Forty cases of invasive pneumococcal disease were identified. Estimated invasive pneumococcal disease incidence was 17.8/100,000 with incidence being highest among children aged 6 months to <12 months (49.9/100,000). Clinical pneumonia syndrome was the most frequent diagnosis (12.5/100,000). Pneumococcal serotypes included: 6A (n=6, 16.7%); 14 (n=5, 13.9%); 5 (n=4, 11.1%); 6B (n=4, 11.1%); 1, 18C, and 19A (n=3 each, 8.3%); 9V (n=2, 5.6%); and 3, 4, 10C, 18A, 18F, and 19F (n=1 each, 2.8%). Serotypes 6A, 14, 6B, 1, 18C, 19A, 9V, 4, 10C, and 18A showed antibiotic resistance. Clinical pneumonia incidence was 2109/100,000, with incidence being highest among children aged 28 days to <6 months (5033/100,000). Chest radiograph-confirmed pneumonia incidence was 1114/100,000, with incidence being highest among children aged 28 days to <6 months (2413/100,000). CONCLUSIONS: Invasive pneumococcal disease and pneumonia were found to be common causes of morbidity in young children living in South Bangalore, India.

Keywords
  • pneumococcal disease,
  • pneumonia,
  • children,
  • India,
  • Streptococcus pneumoniae
Publication Date
March, 2015
Citation Information
R Nisarga, R Premalatha, None Shivananda, KL Ravikumar, et al.. "Hospital-based Surveillance of Invasive Pneumococcal Disease and Pneumonia in South Bangalore, India." Indian Pediatr. Vol. 52 Iss. 3 (2015)
Available at: http://works.bepress.com/paul_kilgore/3/