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Challenges in evaluating surgical innovation
  • Patrick L Ergina, McGill University Faculty of Medicine
  • Jonathan A Cook, University of Aberdeen
  • Jane M Blazeby, University of Bristol
  • Isabelle Boutron, University of Oxford
  • Pierre-Alain Clavien, University Hospital, Zurich
  • Barnaby C Reeves, University of Bristol
  • Christoph M Seiler, University Hospital of Heidelberg
  • Paul P. Glasziou, Bond University
Date of this Version
Document Type
Journal Article
Publication Details

Published version

Ergina P.L., Cook JA, Blazeby J.M., Boutron I., Clavien P.A., Reeves B.C., Seiler C.M. & the Balliol Collaboration. (2009). Challenges in evaluating surgical innovation. Lancet, 374(9695), 1097-1104

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© Copyright Elsevier, 2009

Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide. In this report, the second of three on surgical innovation and evaluation, we discuss obstacles related to the study design of randomised controlled trials and non-randomised studies assessing surgical interventions. We also describe the issues related to the nature of surgical procedures-for example, their complexity, surgeon-related factors, and the range of outcomes. Although difficult, surgical evaluation is achievable and necessary. Solutions tailored to surgical research and a framework for generating evidence on which to base surgical practice are essential.
Citation Information
Patrick L Ergina, Jonathan A Cook, Jane M Blazeby, Isabelle Boutron, et al.. "Challenges in evaluating surgical innovation" Lancet Vol. 364 Iss. 9695 (2009) p. 1097 - 1104 ISSN: 1474-547X
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