Minimal interventions to decrease long-term use of benzodiazepines in primary care: A systematic review and meta-analysisBritish Journal of General Practice
Date of this Version9-1-2011
Document TypeJournal Article
AbstractBackground: Long-term use of benzodiazepines (BZDs) is common. Not only is such use ineffective, but it also has several risks in addition to dependence, and remains a significant problem among the older population.Aim: To systematically review randomised controlled trials that evaluate the effectiveness of minimal interventions to reduce the long-term use of BZDs in primary care.Design and setting: Systematic review and meta-analysis of randomised controlled trials in UK general practices.Method: Cochrane Central, MEDLINE, and Embase (1967-2010) were searched for trials of minimal interventions (such as a single letter or one consultation from a GP) for patients in primary care with long-term (>3 months) BZD use. Pooled risk differences were calculated with 95% confidence intervals.Results: From 646 potentially relevant abstracts, three studies (615 patients) met all the inclusion criteria. The pooled risk ratio showed a significant reduction/cessation in BZD consumption in the minimal intervention groups compared to usual care (risk ratio [RR] = 2.1, 95% confidence interval [CI] = 1.5 to 2.9, PConclusion: A brief intervention in the form of either a letter or a single consultation by GPs, for long-term users of BZD, is an effective and efficient strategy to decrease or stop their medication, without causing adverse consequences.
Citation InformationKayalvili Mugunthan, Treasure McGuire and Paul P. Glasziou. "Minimal interventions to decrease long-term use of benzodiazepines in primary care: A systematic review and meta-analysis" British Journal of General Practice Vol. 61 Iss. 590 (2011) p. e573 - e578 ISSN: 1478-5242
Available at: http://works.bepress.com/paul_glasziou/56/