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Article
Characterization of a pulsatile rotary total artificial heart
Artificial Organs
  • Patrick L. Jurney, San Jose State University
  • Jeremy J. Glynn, Abbott Laboratories
  • Igor V. Dykan, OHSU School of Medicine
  • Matthew W. Hagen, OHSU School of Medicine
  • Sanjiv Kaul, OHSU School of Medicine
  • Richard K. Wampler, OHSU School of Medicine
  • Monica T. Hinds, OHSU School of Medicine
  • George D. Giraud, OHSU School of Medicine
Publication Date
2-1-2021
Document Type
Article
DOI
10.1111/aor.13810
Abstract

This article describes the properties and performance of a rotary total artificial heart (TAH) that produces inherently pulsatile flow. The hydraulic performance of the TAH was characterized using a mock circulatory loop to simulate four physiologically relevant conditions: baseline flow, increased flow, systemic hypertension, and pulmonary hypertension. The pump has a variable shuttle rate (beats per minute), percentage dwell time, and angular velocity on either side (revolutions per minute), which allows for full control of the flow rate and pulsatility over a range of healthy and pathologic pressures and flow rates. The end-to-end length and displacement volume of the TAH are 9.8 cm and 130 mL, respectively, allowing it to fit in smaller chest cavities including those of smaller adults and juvenile humans.

Funding Number
R01 HL144113
Funding Sponsor
National Institutes of Health
Keywords
  • cardiovascular devices,
  • heart failure,
  • total artificial heart
Citation Information
Patrick L. Jurney, Jeremy J. Glynn, Igor V. Dykan, Matthew W. Hagen, et al.. "Characterization of a pulsatile rotary total artificial heart" Artificial Organs Vol. 45 Iss. 2 (2021) p. 135 - 142
Available at: http://works.bepress.com/patrick-jurney/28/