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A Case of Bilateral Renal Oncocytomas in the Setting of Birt-Hogg-Dube Syndrome
  • Brian Covello, HCA Healthcare
  • Sean Kaufman, HCA Healthcare
  • Elizabeth Whittington, HCA Healthcare
  • Orlando Enrizo, HCA Healthcare
East Florida
Aventura Hospital and Medical Center
Document Type
Case Report
Publication Date
  • Birt-Hogg-Dube syndrome,
  • Bilateral renal oncocytomas

Birt-Hogg-Dube syndrome is a rare autosomal dominant disorder characterized by pulmonary cysts, renal tumors, and dermal lesions. This syndrome results from a mutation in the gene folliculin, located on chromosome 17p11.2. Herein, a case is described in which the presence of bilateral renal oncocytomas led to the diagnosis of Birt-Hogg-Dube syndrome via an interdisciplinary effort by radiology, pathology, and primary care medicine. No radiographic features alone are sufficient to confirm the diagnosis of Birt-Hogg-Dube. A high index of suspicion must be maintained by both the pathologist and radiologist in the appropriate clinical setting.

Publisher or Conference
Radiology Case Reports
Citation Information
Covello B, Kaufman S, Whittington E, Enrizo O. A case of bilateral renal oncocytomas in the setting of Birt-Hogg-Dube syndrome. Radiol Case Rep. 2021;16(6):1249-1254.