© 2013 IEEE. Emerging technologies rapidly change the essential qualities of modern societies in terms of smart environments. To utilize the surrounding environment data, tiny sensing devices and smart gateways are highly involved. It has been used to collect and analyze the real-time data remotely in all Industrial Internet of Things (IIoT). Since the IIoT environment gathers and transmits the data over insecure public networks, a promising solution known as authentication and key agreement (AKA) is preferred to prevent illegal access. In the medical industry, the Internet of Medical Things (IoM) has become an expert application system. It is used to gather and analyze the physiological parameters of patients. To practically examine the medical sensor-nodes, which are imbedded in the patient's body. It would in turn sense the patient medical information using smart portable devices. Since the patient information is so sensitive to reveal other than a medical professional, the security protection and privacy of medical data are becoming a challenging issue of the IoM. Thus, an anonymity-based user authentication protocol is preferred to resolve the privacy preservation issues in the IoM. In this paper, a Secure and Anonymous Biometric Based User Authentication Scheme (SAB-UAS) is proposed to ensure secure communication in healthcare applications. This paper also proves that an adversary cannot impersonate as a legitimate user to illegally access or revoke the smart handheld card. A formal analysis based on the random-oracle model and resource analysis is provided to show security and resource efficiencies in medical application systems. In addition, the proposed scheme takes a part of the performance analysis to show that it has high-security features to build smart healthcare application systems in the IoM. To this end, experimental analysis has been conducted for the analysis of network parameters using NS3 simulator. The collected results have shown superiority in terms of the packet delivery ratio, end-to-end delay, throughput rates, and routing overhead for the proposed SAB-UAS in comparison to other existing protocols.